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Chloramphenicol is derived from Streptomyces venezuelae and has a broad spectrum of activity against gram-positive and gram-negative bacteria. It is often used for selection in molecular biology with the cyt B gene.
Synonym: | [R-(R*,R*)]-2,2-Dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4- nitrophenyl)ethyl]acetamide, Chloromycetin, CAP |
CAS: | 56-75-7 |
Formula: | C11H12Cl2N2O5 |
Molecular Wt: | 323.13 |
Properties | |
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Form: | Liquid |
Appearance: | Clear, Colorless |
Application: | Antibiotic |
Solubility: | Miscible with Water |
Storage Temp: | -20 °C |
Typical Working Concentration: | Consult the appropriate literature for your plant species and application. |
Other Notes: | Derived from Streptomyces venezuelae. Plant Tissue Culture Tested |
Application Notes
Chloramphenicol is derived from Streptomyces Venezuelae and has a broad spectrum of activity. It is often used for bacterial selection in molecular biology. Chloramphenicol is effective against grampositive and gram-negative bacteria. It functions by binding to the 50S ribosomal unit to prevent aminoacyl tRNA from binding to the ribosome which prevents elongation of protein chain.
References
Sweetman SC (ed), Martindale: The Complete Drug Reference 35. China: Pharmaceutical Press, 2007
Life Technologies (India) Pvt Ltd. 306, Agarwal City Mall, opposite M2K Pitampura, Delhi-110034 (India) Tel # +91-11-4220-8000; 4220-8111; 4220-8222 Fax# +91-11-4220-8444, Mobile# +91-98105-21400, Toll Free# 1800-120-2434 Email# [email protected] |